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In colorectal cancer, tumor cells upregulate the expression of SLC1A3 and GLS by modulating the YTH N6-methyladenosine RNA binding protein 1 (YTHDF1)-GID complex subunit 8 homolog (GID8) signaling pathway, thereby increasing glutamine uptake and catabolism and ultimately supporting sustained tumor proliferation and survival [133]
Takebe G, Yarimizu J, Saito Y, Hayashi T, Nakamura H, Yodoi J, Nagasawa S, Takahashi K
Seek immediate medical attention if you experience severe abdominal pain radiating to the back with nausea or vomiting, as this may indicate acute pancreatitis
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