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used exendin-4, an exendin-based GLP-1 analog, in hyperglycemia-induced bronchial hyperresponsiveness ex vivo, which resulted in bronchodilation that was inhibited by either cAMP-PKA antagonism or GLP-1 RA [90], a result consistent with other findings (Fig

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Moreover, initiatives promoting personalized healthcare approaches are backed by a healthcare expenditure projected to reach USD 50 billion in the next three years, highlighting a significant opportunity for GLP-1 products that accommodate this trend

There are side effects with GLP-1s, which could also be present in the new class of drugs, although drugmakers are hoping they could be less intense