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GLP-1 agonists work primarily through gut-brain signaling and slowed gastric emptying
The effect on stroke is remarkable (and was significant in the trials of both semaglutide and dulaglutide), amounting to an 18% risk reduction, also because the other class of new antidiabetic agents with cardiovascular benefits, the SGLT2-inhibitors, show no a similar effect on stroke (but do have a significant effect on heart failure) [24]
Before starting folic acid, your GP will check your vitamin B12 levels to ensure they are normal, as folic acid can sometimes mask an underlying B12 deficiency.
Heparin subcutaneous injections often come in pre-filled syringes, so it will be easier to administer the medication
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