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[P]atients with diabetes and obesity, which are the reasons for using GLP-1 medications often have existing risk factors for pancreatitis like gallstones, very high triglycerides, heavy alcohol use, or a history of pancreatitis
Side effects vary by individual and dose
Recent trials show that overweight or obese patients saw a 14.9% reduction in body weight after taking once-weekly semaglutide 2.4 mg for 68 weeks, compared to a 2.4% reduction in body weight for the control [24]
Clinical studies show no evidence of metabolic acceleration that would offset the natural decline in energy requirements accompanying weight reduction
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