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As a result, many people do not get the right amount of nutrients they need for the body to function normally
In this sense, prior works have related menstrual cycles variations with gut microbiota, and nowadays it is widely accepted that there are certain microorganisms directly implicated in the metabolism and effects mediated by estrogens and sex hormones, conforming what is designed as the estrobolome [361]
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For autoimmune patients who benefit metabolically from tirzepatide, planning pregnancy requires coordinated timing between optimizing body weight and metabolic health, ensuring autoimmune disease is in remission or well-controlled, washing out tirzepatide with adequate lead time, and transitioning to pregnancy-safe autoimmune medications
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