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To investigate the neural mechanisms of Cagrilintide, next-generation sequencing (NGS) was performed on three key hypothalamic and brainstem regions: the area postrema/nucleus tractus solitarius (AP/NTS), lateral parabrachial nucleus (LPBN), and ventromedial hypothalamus (VMH)

Their functions exhibit significant duality - they not only provide necessary support for early inflammation initiation and tissue regeneration, but also may exacerbate secondary damage due to excessive activation (104)

That receptor lives in two strategically important locations: the hypothalamus and the anterior pituitary