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Indeed, a higher ratio of M1/M2 was observed in synovial fluid from OA knee compared with normal knees, and the ratio was significantly correlated with the KellgrenLawrence grade 49
doi: 10.1123/ijsnem.16.4.405 557 SgrPCeciRListaMPatrizioFSabatiniSFeliciFet al
Cell morphology shifts toward more cuboidal shapes, indicating increased stemness and restored proliferative potential
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