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However, the endogenous antioxidant MnSOD was increased, which may be an adaptation to counteract increased free radicals during ATP synthesis in the OXPHOS complexes
S2CID 54904180
It has also shown cardioprotective activity during ischemia and reperfusion injury
Moreover, despite more semaglutide-treated patients starting at doses higher than the minimal dose and reaching the higher approved maintenance doses (i.e., 10 mg for tirzepatide and 1.7 mg for semaglutide) during follow-up, weight reduction remained greater in the tirzepatide group
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