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Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1

Unlike native alpha-MSH, which degrades in minutes, MT-II incorporates a lactam bridge and D-amino acids that lock it into a bioactive conformation, making it highly resistant to enzymatic breakdown

Tolerance may be reversed by administration of hydrocortisone (Sun & Hanig, 1983

If youre eating far less than usual, meals may need restructuring to fit enough nutrients into smaller portions