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Tirzepatide trials showed similar or slightly higher incidence rates, particularly at higher doses
The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies
E., Powrie, F., Puri, R
This is something to discuss with the pharmacy when considering a compounded tirzepatide prescription
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