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Description

Increased oxidative stress, inflammation and lipotoxicity associated with hyperglycaemia and insulin resistance potentially impair vascular endothelial function and increase endothelial permeability, leading to the penetration of glycated and oxidized low-density lipoprotein (LDL) cholesterol into the endothelium, i.e., initiation of atherosclerosis

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By comparison, prescription GLP-1 drugs increase hormone levels by hundreds of thousands of percent and remain active far longer in the body

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