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The thyroid neoplasm and suicidal ideation signals that are detected for semaglutide do not reach the disproportionality threshold for tirzepatide
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Tirzepatide (Zepbound) targets two hormone pathways (GLP-1 and GIP) while semaglutide (Ozempic) targets only GLP-1
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Their results clearly show the role of glycemic control and the route of insulin administration in the normalization of IGF-1, IGFBP-1, and GH in patients with recent-onset T1DM
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