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Before tirzepatide, Lilly was developing its own GLP-1-only agonists (e.g., dulaglutide) and amylin analogs, and it launched baricitinib/therapies in inflammation
Okano, N
Access this article Similar content being viewed by others Abbreviations AKG: -Ketoglutarate ASCT2: Alanine, Serine, Cysteine Transporter 2 CRC: Colorectal carcinoma ccRCC: Clear cell renal cell carcinoma ER: Estrogen receptor Gln: Glutamine GS: Glutamine synthetase GLUD: Glutamate dehydrogenase GLS: Glutaminase isoenzyme GLS2: Glutaminase 2 isoenzyme GSH: Glutathione HCC: Hepatocellular carcinoma HNSCC: Head and neck squamous cell carcinoma LAT1: Large amino acid transporter mTOR: Mammalian target of rapamycin NSCLC: Non-small cell lung cancer ROS: Reactive oxygen species SNAT: Sodium-coupled neutral amino acid transporter SLC1A5: Solute-linked carrier family A1 member 5 References DeBerardinis RJ, Chandel NS (2016) Fundamentals of cancer metabolism
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