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CJC-1295 extends growth-hormone pulse duration by increasing the half-life of GHRH, resulting in steady GH release

A single such study, however striking, does not meet the bar for a validated life-extension claim

In contrast to antipsychotic agents, which predominantly alleviate positive symptoms of schizophrenia, PDE1B and PDE10A inhibitors hold promise in addressing the broader symptomatology, including the negative and cognitive symptoms that remain inadequately managed by current therapies (Sadeghi et al., 2023)

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