A milder, less common type happens in older infants and children Most patients with CACT Deficiency Disorder have a severe disease presenting within the first 48 hours of life as low blood sugar with ketonic bodies (hypoketotic hypoglycemia), high ammonia (hyperammonemia) levels in the blood, increased heart muscle (cardiomyopathy), and abnormal heart rhythm (arrhythmias), as well as skeletal muscle damage, liver problems, and low temperature (hypothermia) Neurological involvement, seizures, and developmental delay are also present
According to the SmPC, no dose adjustment is required for patients with renal impairment, including those with end-stage renal disease
Overview of the TrimRx Telehealth Evaluation and Prescription Process According to the company's published FAQ and process descriptions, the TrimRx program begins with a digital medical intake questionnaire designed to collect information about health history, current medications, weight management goals, and other relevant health factors
Mazdutide and tirzepatide both target weight loss as a primary outcome, addressing the global obesity epidemic impacting 1 in 8 people