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GLP-1R mRNA and GLP-1 immunoreactivity was detected in the VTA and NAc, as well as other reward associated areas including lateral hypothalamus, lateral habenula, hippocampus, and substantia nigra (Merchenthaler et al., Afferent and efferent innervation of the hindbrain GLP-1-producing neurons Unlike many of its gut or fat hormone counterparts (ghrelin or leptin) for which there is little evidence of central production, GLP-1 can be made in the brain

Consult your healthcare provider before using if pregnant or nursing

Prediabetes: Individuals with prediabetes have elevated blood sugar but not yet to the level of type 2 diabetes

The DCCT Research Group