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Moreover, clinically-relevant resistance phenotypes may arise through coordinated modulation of a limited number of hub pathwayssuch as redox regulation, metabolic adaptability, and DNA repairconsistent with the recurrent enrichment of GSH metabolism and replication/repairrelated signatures observed in this study

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GLP-1 medications, already used for treatment of obesity and type 2 diabetes, will expand into treatment for other chronic diseases such as heart health, kidney disease and addiction, according to the panel

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