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However, when compared to traditional orally administrated drugs, the pharmacokinetic properties of L-carnitine are complex, since it exhibits poor intestinal absorption and bioavailability, very high renal clearance, and uptake into tissues through a high affinity transporter [13]
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Other oral GLP-1 medicines such as orforglipron are still being studied and should not be treated as available UK weight-loss treatments unless they become licensed
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