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Diabetes lowers exposure by about 15% and blunts the downstream response. Lean, metabolically healthy users sit outside every efficacy trial
We first profiled X(GD) (Extended Data Fig
We would not expect a close match to the clinically observed percentage changes because we are comparing intracellular model changes to blood measurements
Studies have led to the free radical theory of human diseases and to the advancement of nutritional therapies to improve GSH status under various pathological conditions
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