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Comment Occur spontaneously with increased incidence in older rodents and following treatment with carcinogenic and hepatotoxic xenobiotics (Bannasch and Zerban 1990

For patients with IDH (WT)/TET2 (WT) myeloid leukemia, a high level of BCAT1 is a strong predictor of worse survival outcomes, and the BCAT1 level significantly increases on disease relapse (Raffel et al., 2017)