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doi: 10.3724/abbs.2024232 53 NiuWLiuXDengBHongTWangCYanYet al

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The mechanisms by which certain medications bring about oral mucosal melanin hyperpigmentation include upregulation of tyrosinase activity, deposition of complexes of the drug with pre-existing melanin in the mucosa, or induction of local inflammatory reactions with the triggering of melanin production [11, 38]

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Glutathione may interact with some medications

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Chiechio S, Copani A, Nicoletti F, Gereau RW 4th

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