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Children with rare mutations in the CBS or MTR genes can have neural tube defects, early atherosclerosis, or neurological effects.[ref] Related article : MTHFR and the methylation cycle Sex, age, and smoking: Men tend to have higher homocysteine levels than women, and homocysteine levels in both sexes tend to increase slightly with age

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Moreover in BALB/c mice, inclusion of GSH in the drinking water decreased viral titer in both lung and trachea homogenates after intranasal inoculation with a mouse-adapted influenza strain A/X-31 ( Our group demonstrated that GSH was able to inhibit also HIV expression in human macrophages at late stages and this was related to the selective decrease of specific glycoproteins, such as gp120, which are notably rich in disulfide bonds (Garaci et al., 1997)