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"If you don't get good guidance, you're not going to see the optimal effects and then if you don't get good guidance when you lose access or want to adapt your dose, that can really worsen the rebound weight gain and all the negative aspects of coming off those medicines." Dr
Biochemical Society transactions 10 , 7879 (1982)
As of August 2025, the MDL for GLP-1 product liability cases reported ~2,190 pending matters, with over 1,800 active cases earlier in the year
However, the FDA and European Association for the Study of the Liver (EASL) have voiced several safety concerns that have prevented any enthusiastic support for its wide clinical use
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