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Evaluation includes a physician consultation, health history review, and lab testing
Colchicine, Neomycin, Aminosalicylic Acid, H2-blockers (e.g., Ranitidine), and Proton Pump Inhibitors (PPIs, e.g., Omeprazole): These oral medications can all interfere with the intestinal absorption of dietary B12, making the need for injectable B12 more pronounced
Starting with low doses helps minimize side effects and supports gradual results
DNA synthesis and cell metabolism Intracellular conversion of vitamin B 12 to two active coenzymes, in mitochondria and adenosylcobalamin in the cytoplasm, is necessary for the homeostasis of methylmalonic acid and homocysteine, respectively
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