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The dose-response data show a weight effect that flattens toward the top of the range alongside dose-dependent gastrointestinal adverse events, which is consistent with a tolerability-driven choice but that reading is an inference drawn here, not a documented rationale, and Novo Nordisk has published no dose-selection statement
Frontiers in Pharmacology, 13, 1026182
Among these, the Lactococcus and Streptococcus genera are generally more abundant than those such as Lacticaseibacillus and Lactobacillus (144)
Weight loss should be gradual, aiming for 0.5-1 kg per week, achieved through a combination of reduced calorie intake and increased physical activity
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