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In a randomized placebo-controlled pilot study, researchers examined whether adding phentermine to patients already on liraglutide (a GLP-1 agonist) for one year would produce additional weight loss
Over time, the genome becomes increasingly dysregulated: DNA regions that should be silent become noisy, protective genes are switched off, and chromatin, the scaffold of DNA wrapped around histones (imagine them like packaging bundles), becomes condensed and brittle, losing its flexibility
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