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This approach sacrifices convenience but gives you complete control over how much of each peptide you administer
Moreover, given that we detected an increases in the levels of FXR-antagonistic BAs, but did not observe an elevation in the levels of TGR5-agonistic BAs and cAMP, we then speculate that FXR-mediated pathway rather than TGR5-mediated pathway was critically involved in the regulation of GLP-1 by T3 treatment in mice
However, the drug's complete safety profile, long-term effects, and drug interaction data remain under investigation
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