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This signaling cascade induces CXCL1 secretion by gastric cancer cells, driving recruitment of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs), CD8 T-cell exhaustion, and resistance to ICIs
Antioxid Redox Signal 30:251294
- 54
Upon interaction with GSH, IR806-PDA is converted into IR806-S-NH, resulting in a spectral shift (from 680 to 820 nm) and generating ratiometric photoacoustic signals that correlate with GSH levels
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