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Abstract Tumor microenvironment is intrinsically hypoxic with abundant hypoxia-inducible factors-1 (HIF-1), a primary regulator of the cellular response to hypoxia and various stresses imposed on the tumor cells
Generally, B12 injections are administered every 3 to 7 days, in treatment cycles of 3 weeks or more, as recommended by the doctor
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2013 Jun 10;184:1-5
