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The precise mechanism underlying ferroptosis is still unknown, but it is known that altered iron metabolism, glutathione (GSH) depletion, GPX4 inactivation, and increased PUFA peroxidation by ROS play key roles in its onset and progression [80, 81]
10.1111/j.2040-1124.2010.00083.x 124 TiwariV.KuhadA.ChopraK
& Kass, M
Because it can aid in neutralizing oxidative stress, many clinics offer glutathione as an injection, or supplementing IV drips with the antioxidant during cold and flu season
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