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[3] It is important to note that retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA) (MHRA medicines licensing database, accessed 2025
Investigators from the National Health and Nutrition Examination Survey estimate that 136.8 million adults met the criteria for at least one of three approved indications for semaglutide diabetes, weight management, or secondary cardiovascular disease prevention:
Lu Y, Tonissen KF, Di Trapani G
They added that there is also overlap between the brain mechanisms that regulate overeating and those that contribute to the development and maintenance of substance use disorders, including AUD
