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The successful incorporation of the MLC enhancer was confirmed in F0 mice by PCR across the 3 and 5 junctions ( Table 1 ) and was confirmed in their offspring by Southern blot analysis (Figs 3a and 5a)
Por eso, el tratamiento es escalonado: se comienza con 2,5 mg semanales para que el cuerpo se adapte y luego se aumenta progresivamente la dosis segn la tolerancia y la respuesta del paciente
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