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Varma V, Yao-Borengasser A, Rasouli N, Nolen GT, Phanavanh B, Starks T, et al
Stopping a GLP-1 cold produces rebound hunger that can undo months of progress in weeks
Most patients regain 50% of their lost weight within one year if they stop taking semaglutide
Key nutritional priorities during the switch include maintaining protein intake at 1 gram per pound of lean body mass (this is critical for preserving muscle), keeping fiber intake above 25 grams daily for gut health and satiety, staying hydrated with at least 64 ounces of water daily (more if you experience GI symptoms), and avoiding alcohol during the first 4 weeks as it amplifies both nausea and blood sugar instability
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