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These modifications result in a longer half-life, allowing for once-weekly dosing rather than daily administration
Both can cause nausea, GI upset, or constipation, but I see liraglutide patients more often report daily low-grade nausea, whereas semaglutide tends to cause more pronounced symptoms early on that taper with dose titration
CJC-1295 comes in two forms: with DAC (long-acting, 8-day half-life) and without DAC (short-acting, also called Modified GRF 1-29)
Stay hydrated, rest, and eat smaller, bland meals if hunger returns
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