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An analysis of 12 studies discovered that people who took an alpha-lipoic acid supplement lost an average of 1.52 pounds (0.69 kg) more than those taking a placebo over an average of 14 weeks ( In the same analysis, alpha-lipoic acid did not significantly affect waist circumference

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Ozempic (semaglutide) and Mounjaro (tirzepatide) are FDA-approved primarily for the treatment of adults with type 2 diabetes mellitus to improve blood sugar control and reduce the risk of major cardiovascular events in adults with type 2 diabetes and established cardiovascular disease