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IV magnesium can support muscle relaxation, reduce cramping, improve sleep quality, and help with stress regulation
If side effects become intolerable at any dose level, dropping back to the previous dose for two to four additional weeks before attempting escalation again often allows successful progression
In landmark trials such as SUSTAIN-6 and PIONEER-6, semaglutide demonstrated a significant reduction in major adverse cardiovascular events, including cardiovascular death, non-fatal heart attacks, and strokes, compared to placebo or standard care
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