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Another GoF variant, A316T, shows a 2-fold increase in cAMP accumulation ( 2+ mobilization (which is essential for insulin secretion)
Evidence level: Limited human evidence Sources: PCO-02 safety and pharmacokinetics trial, Intra-articular injection of BPC 157 for multiple types of knee pain How to read this: The registry record has no efficacy result, and the published knee report is retrospective, uncontrolled, and based on telephone follow-up
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