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Tirzepatide differs from GLP-1RAs in that, in addition to agonizing the GLP-1R, this drug also acts as a GIPR agonist, providing direct effects on white adipose tissue that may further benefit MASH histology beyond glycemic control and weight loss [52]
Likewise, since Ozempic deliberately slows stomach emptying, these high-fat foods "have even more time to hang around and upset your gut"
For the typical adult carrying extra weight and otherwise healthy, the side effect story is mild, manageable, and mostly front-loaded into the first weeks
Its important for people with type 2 diabetes to manage blood sugar levels during and after treatment
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