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They may also recommend GLP-1s to individuals who are at increased risk for cardiovascular disease, since some studies show these medications can help protect heart health

Carnitine/acetylcarnitine also have potentially positive effects on hormonal and metabolic parameters in patients with reproductive dysfunction, such as polycystic ovary syndrome [86, 87], and these effects may involve a series of complex signal transduction pathways to maintain the homeostasis of the endocrine system [88]

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These trials will refine our understanding of optimal cagrilintide dosing across diverse contexts and potentially identify subpopulations who benefit most from this approach