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A calorie deficit focuses on total energy intake regardless of macronutrient composition, whereas low-carbohydrate diets restrict a specific food group
Access to weight-loss medicines depends on NICE guidance and local commissioning arrangements
Mounjaro (tirzepatide) received NICE approval in 2025 under TA1026 for adults with obesity who meet similar criteria but have either not responded adequately to other treatments or have concurrent type 2 diabetes
Adverse effects, inadequate treatment, or a delayed detection of underlying issues can result from improper use
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