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Description

21 FDA (2022)

Although NE is present in the intestinal lumen 24 , it is not clear whether NE in the intestinal tissue is released into the intestinal lumen and there appear to be no reports of NE-mediated increases in E

This short half-life made therapeutic use challenging for decades, until researchers began developing GIP receptor agonists and dual/triple agonists that could resist degradation or mimic its effects more efficiently