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A meta-analysis was done which indicates that albiglutide is linked to a higher risk of early-stage DR compared to placebo, while showing a reduced risk of late-stage DR compared to insulin (85) Furthermore, the other six FDA-approved GLP-1RAs do not demonstrate a statistically significant association with DR

Significantly more potent and better tolerated than arsenic trioxide, Darinaparsin showed encouraging responses in T-cell lymphoma (Hosein et al., 2012) and AML (Nielsen et al., 2013) patients

What weve learned is that GLP-1 acts on widely distributed but metabolically relevant brain circuitry

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