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Results and discussion 1
While GLP-1 drugs were originally designed for diabetes and obesity, clinical data show they significantly reduce markers of inflammation (like C-reactive protein, or CRP) remarkably quickly, usually long before any significant weight loss occurs
Farnesoid X receptor interacts with cAMP response element binding protein to modulate glucagon-like peptide-1 (736) amide secretion by intestinal L cell
The Diabetes Prevention Programme, a large RCT comparing Metformin, ILI and placebo, indicated that after 21 years of follow-up, there was no significant reduction in cancer incidence comparing ILI to placebo (RR 0.96, 95% CI = 0.791.18) [14]
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