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To explore whether cell sorting operation can highlight the biological function of the target gene, we performed a cell proliferation assay with K-562 cells transfected with the plasmid encoding the ATP6AP1L gene, with or without enrichment by affinity cell sorting

In the context of a restricted assay-format, in which implication of free LASSS can be excluded, the outcomes may provide critical insights towards understanding of an underlying LASSS-driven mechanism

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Once active, L-5-MTHF works alongside Vitamin B12 to convert homocysteine into methionine, which is then used to produce S-adenosylmethionine (SAMe), the body's universal methyl donor