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& Valentino, R
L.ThakkerD
has a very high affinity for the phosphorous atom of oragnophosphates and can cause the bond between the organophosphate agent and the cholinesterase to hydrolyze if the complex has not aged Pralidoxime's effect on non-aged organophosphate-enzyme complexes causes a reactivation of cholinesterase activity
Replenishing systemic stores may restore normal oxidative capacity and improves metabolic homeostasis in deficient states
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