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In contrast to common obesity, where cardiovascular risk reduction drives intervention, the main rationale for treatment in MC4R -deficient patients shifts toward alleviating mechanical complications (e.g., sleep apnea, osteoarthritis), preventing diabetes (hyperinsulinemia is common despite relative euglycemia), and improving quality of life [30]
Los resultados mostraron una reduccin de peso notablemente mayor en los participantes tratados con liraglutide en comparacin con aquellos que recibieron un placebo
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