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While studies have not explicitly addressed whether GLP-1 drugs directly affect depression symptoms in humans, animal studies have measured decreased depression and anxiety
Cell Mol Biol (Noisy-Le-Grand) 64:16 Patel SP, Sullivan PG, Lyttle TS, Magnuson DS, Rabchevsky AG (2012) Acetyl-l-carnitine treatment following spinal cord injury improves mitochondrial function correlated with remarkable tissue sparing and functional recovery
they are classic hangover symptoms caused largely by dehydration and nutrient depletion
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