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Red blood cells, as well as cells of the brain, liver, kidneys, and the lining of the small intestine, do not have insulin receptors on their cell membranes and do not require insulin for glucose uptake

Besides database shortcomings, the enrichment is limited by the sampling and scoring function of the docking algorithm, as docking methods often prioritize speed over precision, leading to approximations in both the sampling of conformations and scoring, which may hinder the identification of true positive targets

Ranji Cui, [email protected] This article was submitted to Neuropharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Serious allergies usually involve hives, swelling, or difficulty breathing, which require immediate medical attention