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In people with type 2 diabetes who also use insulin or insulin-stimulating drugs, such as sulfonylureas, the risk of low blood sugar, also called hypoglycemia, may be increased, so the doses of those medicines may need to be lowered
So pay attention when designing them
Consider earlier administration (3+ hours before bed) to allow cortisol-modulating effects to establish before sleep pressure builds
If you already have a history of gallbladder symptoms, Mounjaro may worsen them
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