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In mice with intact gut microbiota, dietary supplementation of TMAO, carnitine, or high choline can significantly reduce the reverse transport of cholesterol in the body, thereby aggravating the progression of atherosclerosis in mice (35)

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Artificially synthesized carnitine includes L-carnitine, D-carnitine, and DL-carnitine, and only L-carnitine has physiological activities

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2001 Mar;280(3):C415-22

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Clinical studies have indicated that L-carnitine maintained healthy cardiac enzymes including lipid peroxides and lactate dehydrogenase

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